What this Mexico City & Panama City page shows
This page compares the full metro areas of Mexico City (MEX, NLU) and Panama City (PTY) and lists every destination both cities can reach on a nonstop flight: 46 in all, across 22 countries and 5 regions. For each one you can see the flight time and distance from MEX and from PTY, so the trade-off between the two legs is clear at a glance.
Use the map to see how far the options spread, then check the meet-in-the-middle pick (San Salvador has the smallest gap in flight distance here) before opening the full table to sort all 46 shared routes. To filter by month and check live fares, open the Midway app with Mexico City and Panama City already loaded.
Where you can both fly
Every marker is a destination with nonstop service from both Mexico City and Panama City. The spread runs from Cartagena close by to Amsterdam at the far edge, so you can gauge whether a short hop or a long-haul meet-up makes more sense.
All shared destinations
Each row is a destination both cities reach nonstop. The two right-hand columns give the flight time and distance from MEX and from PTY. When those two legs are close, the trip splits evenly between Mexico City and Panama City. Open the full table in Midway to sort by either leg or filter by month.
Where in the world
Shared destinations grouped by region — 46 in total across 5 regions.
Year-round or seasonal
93% of these routes fly year-round, with 3 running only in certain seasons. If your meet-up date is flexible you have the full set to choose from; if it is fixed, lean toward the year-round destinations so you are not counting on a route that may not be flying that month.
Related Routes
Frequently asked questions
How many nonstop destinations do Mexico City and Panama City share?
Travelers from Mexico City and Panama City have 46 common nonstop options, covering 5 regions and 22 countries.
What is the closest place both Mexico City and Panama City can fly to nonstop?
Cartagena is the closest shared nonstop destination for Mexico City and Panama City.
Where should travelers from Mexico City and Panama City meet halfway?
San Salvador is the most balanced shared destination, with the smallest difference in flight distance from the two cities.
What is the farthest shared nonstop destination from Mexico City and Panama City?
Amsterdam is the farthest destination both Mexico City and Panama City can reach nonstop.
Open Mexico City and Panama City in Midway
Filter by month, distance, flight time, country and region, see prices from each city, and send the link to your group.
Last updated: October 22, 2026